Caracterización Clínica y Epidemiológica de los Pacientes con COVID-19 en un centro ambulatorio de Quito
DOI:
https://doi.org/10.31790/inspilip.v8i26.670Palabras clave:
COVID-19, Comorbilidades, Epidemiología ClínicaResumen
Introducción: Se presentan las características clínicas y epidemiológicasde los pacientes diagnosticados con COVID-19 en el centro ambulatorioEl Batán, de enero-marzo de 2021. Objetivo: Describir las característicasclínicas y epidemiológicas de los pacientes diagnosticados y atendidos conCOVID-19. Métodos: Estudio observacional, transversal, donde de tomaron431 casos que dieron positivo para COVID-19. Resultados: De 431 casospositivos, el 52.9 % fueron hombres y la edad media fue de 40.3 años. Lamayoría de los casos fueron de 26 a 45 años, siendo el personal administrativoy de atención al público los más afectados ocupacionalmente. Se observaroncomorbilidades como hipertensión arterial, diabetes, hipotiroidismo ygastritis, además de condiciones más graves como cáncer, cardiopatíaisquémica y VIH en algunos pacientes. Los síntomas más frecuentes fuerontos, odinofagia y anosmia-hiposmia. Conclusiones: Se determinó que el48.5 % de los pacientes tenían un riesgo clínico bajo, el 33.2 % un riesgomoderado y el 18.3 % un riesgo alto de agravamiento. Los factores queaumentaron el riesgo de presentar un cuadro clínico grave incluyeron sermujer, tener entre 20 y 39 años, ser personal sanitario, tener entre 40 y 64años o más de 65 años, ser hombre jubilado y tener comorbilidades comodiabetes, hipertensión arterial e insuficiencia cardiaca.
Citas
Roa Mena M. • Gráfico: El virus que se ha extendido por todo el mundo | Statista [Internet]. 2021 [cited 2021 Oct 19]. Available from: https://es.statista.com/grafico/20628/paises-con-casos-del-coronavirus-covid-19/
Kwok KO, Huang Y, Tsoi MTF, Tang A, Wong SYS, Wei WI, et al. Epidemiology, clinical spectrum, viral kinetics and impact of COVID‐19 in the Asia‐Pacific region. Respirology [Internet]. 2021 Apr 1 [cited 2022 Mar 6];26(4):322. Available from: /pmc/articles/PMC8207122/
Larsen F. El virus que torció la historia de Italia – Riberas [Internet]. 2020 [cited 2021 Oct 19]. Available from: https://riberas.uner.edu.ar/el-virus-que-torcio-la-historia-de-italia/
Secretaría General de Comunicación de la Presidencia. Se registra el primer caso de coronavirus en Ecuador – Secretaría General de Comunicación de la Presidencia [Internet]. 2020 [cited 2021 Oct 5]. Available from: https://www.comunicacion.gob.ec/se-registra-el-primer-caso-de-coronavirus-en-ecuador/
Li L quan, Huang T, Wang Y qing, Wang Z ping, Liang Y, Huang T bi, et al. COVID-19 patients’ clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol [Internet]. 2020 Jun 1 [cited 2022 Oct 7];92(6):577–83. Available from: https://pubmed.ncbi.nlm.nih.gov/32162702/
Tene L, Bergroth T, Eisenberg A, David SS Ben, Chodick G. Risk factors, health outcomes, healthcare services utilization, and direct medical costs of patients with long COVID. International Journal of Infectious Diseases. 2023 Mar 1;128:3–10.
X F, S L, H Y, P W, Y Z, Z C, et al. Epidemiological, comorbidity factors with severity and prognosis of COVID-19: a systematic review and meta-analysis. Aging [Internet]. 2020 [cited 2021 Oct 6];12(13):12493–503. Available from: https://pubmed.ncbi.nlm.nih.gov/32658868/
Li X, Zhong X, Wang Y, Zeng X, Luo T, Liu Q. Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis. PLoS One [Internet]. 2021 May 1 [cited 2022 Oct 7];16(5). Available from: https://pubmed.ncbi.nlm.nih.gov/33939733/
Israfil SMH, Sarker MMR, Rashid PT, Talukder AA, Kawsar KA, Khan F, et al. Clinical Characteristics and Diagnostic Challenges of COVID-19: An Update From the Global Perspective. Front Public Health [Internet]. 2021 Jan 11 [cited 2022 Oct 7];8. Available from: https://pubmed.ncbi.nlm.nih.gov/33505949/
Singhal S, Kumar P, Singh S, Saha S, Dey AB. Clinical features and outcomes of COVID-19 in older adults: a systematic review and meta-analysis. BMC Geriatr [Internet]. 2021 Dec 1 [cited 2022 Oct 7];21(1). Available from: https://pubmed.ncbi.nlm.nih.gov/34011269/
Li J, Huang DQ, Biyao |, Mpp Z, Yang H, Wan |, et al. Epidemiology of COVID-19: A systematic review and meta-analysis of clinical characteristics, risk factors, and outcomes. J Med Virol [Internet]. 2021 [cited 2022 Oct 7];93:1449–58. Available from: http://www.prisma-statement.org/
Kim Y, Parekh MA, Li X, Huang Y, Zhang GQ, Manwani B. Age and sex-specific stroke epidemiology in COVID-19. Frontiers in Stroke. 2023 Jun 7;2:1172854.
Strandberg TE, Pentti J, Kivimäki M. Sex Difference in Serious Infections: Not only COVID-19. Epidemiology [Internet]. 2021 Nov 1 [cited 2024 May 19];32(6):E26–7. Available from: https://journals.lww.com/epidem/fulltext/2021/11000/sex_difference_in_serious_infections__not_only.19.aspx
Atkins JL, Masoli JAH, Delgado J, Pilling LC, Kuo CL, Kuchel GA, et al. Preexisting Comorbidities Predicting Severe Covid-19 in Older Adults in the UK Biobank Community Cohort. medRxiv [Internet]. 2020 Jan 1;2020.05.06.20092700. Available from: http://medrxiv.org/content/early/2020/05/08/2020.05.06.20092700.abstract
Reilev M, Kristensen KB, Pottegård A, Lund LC, Hallas J, Ernst MT, et al. Characteristics and predictors of hospitalization and death in the first 9,519 cases with a positive RT-PCR test for SARS-CoV-2 in Denmark: A nationwide cohort. medRxiv [Internet]. 2020 Jan 1;2020.05.24.20111823. Available from: http://medrxiv.org/content/early/2020/05/26/2020.05.24.20111823.abstract
Bajgain KT, Badal S, Bajgain BB, Santana MJ. Prevalence of comorbidities among individuals with COVID-19: A rapid review of current literature. Am J Infect Control [Internet]. 2021 Feb 1 [cited 2022 Oct 7];49(2):238–46. Available from: https://pubmed.ncbi.nlm.nih.gov/32659414/
Elezkurtaj S, Greuel S, Ihlow J, Michaelis EG, Bischoff P, Kunze CA, et al. Causes of death and comorbidities in hospitalized patients with COVID-19. Scientific Reports 2021 11:1 [Internet]. 2021 Feb 19 [cited 2024 May 19];11(1):1–9. Available from: https://www.nature.com/articles/s41598-021-82862-5
Silaghi-Dumitrescu R, Patrascu I, Lehene M, Bercea I. Comorbidities of COVID-19 Patients. Medicina 2023, Vol 59, Page 1393 [Internet]. 2023 Jul 29 [cited 2024 May 19];59(8):1393. Available from: https://www.mdpi.com/1648-9144/59/8/1393/htm
Callender LA, Curran M, Bates SM, Mairesse M, Weigandt J, Betts CJ. The Impact of Pre-existing Comorbidities and Therapeutic Interventions on COVID-19. Front Immunol [Internet]. 2020 Aug 11 [cited 2024 May 19];11:567283. Available from: www.frontiersin.org
Sahin M, Demirci I, Haymana C, Tasci I, Emral R, Cakal E, et al. The Clinical Characteristics and Outcomes of COVID-19 Patients with Pre-Existing Thyroid Dysfunction: A Nationwide Study. Hormone and Metabolic Research [Internet]. 2023 Jan 1 [cited 2024 May 19];55(1):25–30. Available from: http://www.thieme-connect.com/products/ejournals/html/10.1055/a-1971-8781
Rubin SJS, Falkson SR, Degner NR, Blish C. Clinical characteristics associated with COVID-19 severity in California. J Clin Transl Sci [Internet]. 2021 [cited 2024 May 19];5(1):e3. Available from: https://www.cambridge.org/core/journals/journal-of-clinical-and-translational-science/article/clinical-characteristics-associated-with-covid19-severity-in-california/B58EB9C431C6404D867BF70DBCAEBA19
Zhang J jin, Dong X, Cao Y yuan, Yuan Y dong, Yang Y bin, Yan Y qin, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy [Internet]. 2020 Jul 1 [cited 2024 May 19];75(7):1730–41. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/all.14238
Bergman J, Ballin M, Nordström A, Nordström P. Risk factors for COVID-19 diagnosis, hospitalization, and subsequent all-cause mortality in Sweden: a nationwide study. Eur J Epidemiol [Internet]. 2021 Mar 1 [cited 2024 May 19];36(3):287–98. Available from: https://link.springer.com/article/10.1007/s10654-021-00732-w
Galanis P, Vraka I, Fragkou D, Bilali A, Kaitelidou D. Seroprevalence of SARS-CoV-2 antibodies and associated factors in healthcare workers: a systematic review and meta-analysis. Journal of Hospital Infection. 2021 Feb 1;108:120–34.
Organización Panamericana de la Salud. Módulos de principios de epidemiología para el control de enfermedades, módulo 5: Investigación epidemiológica de campo: aplicación al estudio de brote. Tercera edición. Fernández Quintanilla G, Suarez Agudelo M, Amado y Luarca F, editors. 2017.
Struyf T, Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Leeflang MM, et al. Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19. Cochrane Database of Systematic Reviews. 2022 May 20;2022(5).
Olumade TJ, Uzairue LI. Clinical characteristics of 4499 COVID‐19 patients in Africa: A meta‐analysis. J Med Virol [Internet]. 2021 May 12;93(5):3055–61. Available from: https://onlinelibrary.wiley.com/doi/10.1002/jmv.26848
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